MolBI Goethe University

LOEWE Ub-net

CEF Cluster of Excellence Frankfurt

© 2014 Molecular Bioinformatics @ Goethe-University

Welcome to Molecular Bioinformatics MolBI

MolBI May 2014

Our group was established in March 2010 and works in the field of Bioinformatics & Computational Systems Biology. We are interested in algorithm and method development and applications to answer questions in molecular biology. In this context, we are focusing on modeling and analysis of biochemical systems and computational protein structure analysis.

We are using various methods, such as graph-theory, general network analysis techniques, Boolean networks, Petri net formalism and others, to explore biochemical systems at different levels of abstraction. These systems cover metabolic networks, signal transduction networks, and gene-regulatory networks. Because of the size and complexity of biochemical networks, models of them have to be investigated for their correctness and completeness. Thus, we are interested in network validation techniques and network reduction approaches.

Moreover, we are interested in structural questions of proteins and their topology.

Modeling in Systems BiologyPetri-Net Book: Modeling in Systems Biology